affliction
Definitions
A state of pain, distress, or misery.
Something that causes pain or suffering, such as a physical ailment or disease.
Examples
The elderly man suffered from a chronic affliction that made walking very difficult.
Poverty is a social affliction that requires urgent attention from policymakers.
Despite his physical affliction, he remained optimistic and pursued his dreams with great passion.
Synonyms
ailment disease malady suffering distress misery tribulation